750 research outputs found
Use of cumulative mortality data in patients with acute myocardial infarction for early detection of variation in clinical practice: observational study
OBJECTIVES: Use of cumulative mortality adjusted for
case mix in patients with acute myocardial infarction
for early detection of variation in clinical practice.
DESIGN: Observational study.
SETTING: 20 hospitals across the former Yorkshire
region.
PARTICIPANTS: All 2153 consecutive patients with
confirmed acute myocardial infarction identified
during three months.
MAIN OUTCOME MEASURES: Variable lifeÂadjusted
displays showing cumulative differences between
observed and expected mortality of patients; expected
mortality calculated from risk model based on
admission characteristics of age, heart rate, and
systolic blood pressure.
RESULTS: The performance of two individual hospitals
over three months was examined as an example. One,
the smallest district hospital in the region, had a series
of 30 consecutive patients but had five more deaths
than predicted. The variable lifeÂadjusted display
showed minimal variation from that predicted for the
first 15 patients followed by a run of unexpectedly
high mortality. The second example was the main
tertiary referral centre for the region, which admitted
188 consecutive patients. The display showed a period
of apparently poor performance followed by
substantial improvement, where the plot rose steadily
from a cumulative net lives saved of - 4 to 7. These
variations in patient outcome are unlikely to have
been revealed during conventional audit practice.
CONCLUSIONS: Variable lifeÂadjusted display has been
integrated into surgical care as a graphical display of
riskÂadjusted survival for individual surgeons or centres.
In combination with a simple risk model, it may have a
role in monitoring performance and outcome in
patients with acute myocardial infarction
Long-Time Behavior of Macroscopic Quantum Systems: Commentary Accompanying the English Translation of John von Neumann's 1929 Article on the Quantum Ergodic Theorem
The renewed interest in the foundations of quantum statistical mechanics in
recent years has led us to study John von Neumann's 1929 article on the quantum
ergodic theorem. We have found this almost forgotten article, which until now
has been available only in German, to be a treasure chest, and to be much
misunderstood. In it, von Neumann studied the long-time behavior of macroscopic
quantum systems. While one of the two theorems announced in his title, the one
he calls the "quantum H-theorem", is actually a much weaker statement than
Boltzmann's classical H-theorem, the other theorem, which he calls the "quantum
ergodic theorem", is a beautiful and very non-trivial result. It expresses a
fact we call "normal typicality" and can be summarized as follows: For a
"typical" finite family of commuting macroscopic observables, every initial
wave function from a micro-canonical energy shell so evolves that for
most times in the long run, the joint probability distribution of these
observables obtained from is close to their micro-canonical
distribution.Comment: 34 pages LaTeX, no figures; v2: minor improvements and additions. The
English translation of von Neumann's article is available as arXiv:1003.213
Solidification of Al-Sn-Cu based immiscible alloys under intense shearing
The official published version of the Article can be accessed from the link below - Copyright @ 2009 The Minerals, Metals & Materials Society and ASM InternationalThe growing importance of Al-Sn based alloys as materials for engineering applications
necessitates the development of uniform microstructures with improved performance. Guided by the recently thermodynamically assessed Al-Sn-Cu system, two model immiscible alloys, Al-45Sn-10Cu and Al-20Sn-10Cu, were selected to investigate the effects of intensive melt shearing provided by the novel melt conditioning by advanced shear technology (MCAST) unit on the uniform dispersion of the soft Sn phase in a hard Al matrix. Our experimental results have confirmed that intensive melt shearing is an effective way to achieve fine and uniform
dispersion of the soft phase without macro-demixing, and that such dispersed microstructure can be further refined in alloys with precipitation of the primary Al phase prior to the demixing reaction. In addition, it was found that melt shearing at 200 rpm and 60 seconds will be adequate to produce fine and uniform dispersion of the Sn phase, and that higher shearing speed and prolonged shearing time can only achieve minor further refinement.This work is funded by the EPSRC and
DT
Universality and Critical Phenomena in String Defect Statistics
The idea of biased symmetries to avoid or alleviate cosmological problems
caused by the appearance of some topological defects is familiar in the context
of domain walls, where the defect statistics lend themselves naturally to a
percolation theory description, and for cosmic strings, where the proportion of
infinite strings can be varied or disappear entirely depending on the bias in
the symmetry. In this paper we measure the initial configurational statistics
of a network of string defects after a symmetry-breaking phase transition with
initial bias in the symmetry of the ground state. Using an improved algorithm,
which is useful for a more general class of self-interacting walks on an
infinite lattice, we extend the work in \cite{MHKS} to better statistics and a
different ground state manifold, namely , and explore various different
discretisations. Within the statistical errors, the critical exponents of the
Hagedorn transition are found to be quite possibly universal and identical to
the critical exponents of three-dimensional bond or site percolation. This
improves our understanding of the percolation theory description of defect
statistics after a biased phase transition, as proposed in \cite{MHKS}. We also
find strong evidence that the existence of infinite strings in the Vachaspati
Vilenkin algorithm is generic to all (string-bearing) vacuum manifolds, all
discretisations thereof, and all regular three-dimensional lattices.Comment: 62 pages, plain LaTeX, macro mathsymb.sty included, figures included.
also available on
http://starsky.pcss.maps.susx.ac.uk/groups/pt/preprints/96/96011.ps.g
The Middle Way: East Asian masters studentsâ perceptions of critical argumentation in U.K. universities.
The paper explores the learning experiences of East Asian masters students in dealing with Western academic norms of critical thinking in classroom debate and assignment writing. The research takes a cultural approach, and employs grounded theory and case study methodology, the aims being for students to explain their perceptions of their personal learning journeys. The data suggest that the majority of students interviewed rejected full academic acculturation into Western norms of argumentation. They instead opted for a âMiddle Wayâ that synergizes the traditional cultural academic values held by many East Asian students with those elements of Western academic norms that are perceived to be aligned with these. This is a relatively new area of research which represents a challenge for British lecturers and students
Charged black holes in quadratic gravity
Iterative solutions to fourth-order gravity describing static and
electrically charged black holes are constructed. Obtained solutions are
parametrized by two integration constants which are related to the electric
charge and the exact location of the event horizon. Special emphasis is put on
the extremal black holes. It is explicitly demonstrated that in the extremal
limit, the exact location of the (degenerate) event horizon is given by \rp =
|e|. Similarly to the classical Reissner-Nordstr\"om solution, the
near-horizon geometry of the charged black holes in quadratic gravity, when
expanded into the whole manifold, is simply that of Bertotti and Robinson.
Similar considerations have been carried out for the boundary conditions of
second type which employ the electric charge and the mass of the system as seen
by a distant observer. The relations between results obtained within the
framework of each method are briefly discussed
The Global Forest Transition as a Human Affair
Forests across the world stand at a crossroads where climate and land-use changes are shaping their future. Despite demonstrations of political will and global efforts, forest loss, fragmentation, and degradation continue unabated. No clear evidence exists to suggest that these initiatives are working. A key reason for this apparent ineffectiveness could lie in the failure to recognize the agency of all stakeholders involved. Landscapes do not happen. We shape them. Forest transitions are social and behavioral before they are ecological. Decision makers need to integrate better representations of peopleâs agency in their mental models. A possible pathway to overcome this barrier involves eliciting mental models behind policy decisions to allow better representation of human agency, changing perspectives to better understand divergent points of view, and refining strategies through explicit theories of change. Games can help decision makers in all of these tasks
It Is Hot in the Sun: Antarctic Mosses Have High Temperature Optima for Photosynthesis Despite Cold Climate
The terrestrial flora of Antarcticaâs frozen continent is restricted to sparse ice-free areas and dominated by lichens and bryophytes. These plants frequently battle sub-zero temperatures, extreme winds and reduced water availability; all influencing their ability to survive and grow. Antarctic mosses, however, can have canopy temperatures well above air temperature. At midday, canopy temperatures can exceed 15°C, depending on moss turf water content. In this study, the optimum temperature of photosynthesis was determined for six Antarctic moss species: Bryum pseudotriquetrum, Ceratodon purpureus, Chorisodontium aciphyllum, Polytrichastrum alpinum, Sanionia uncinata, and Schistidium antarctici collected from King George Island (maritime Antarctica) and/ or the Windmill Islands, East Antarctica. Both chlorophyll fluorescence and gas exchange showed maximum values of electron transport rate occurred at canopy temperatures higher than 20°C. The optimum temperature for both net assimilation of CO2 and photoprotective heat dissipation of three East Antarctic species was 20â30°C and at temperatures below 10°C, mesophyll conductance did not significantly differ from 0. Maximum mitochondrial respiration rates occurred at temperatures higher than 35°C and were lower by around 80% at 5°C. Despite the extreme cold conditions that Antarctic mosses face over winter, the photosynthetic apparatus appears optimised to warm temperatures. Our estimation of the total carbon balance suggests that survival in this cold environment may rely on a capacity to maximize photosynthesis for brief periods during summer and minimize respiratory carbon losses in cold conditions.Alicia V. Perera-Castro, Melinda J. Waterman, Johanna D. Turnbull, Michael B. Ashcroft, Ella McKinley, Jennifer R. Watling, Jessica Bramley-Alves, Angelica Casanova-Katny, Gustavo Zuniga, Jaume Flexas, and Sharon A. Robinso
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